"And Jacob was left alone; and there wrestled a man with him until the breaking of day. And when he saw that he touched the hallow of his tigh; and the hollow of Jacob's thigh was out of joint, as he wrestled with him." (Gen. 32:24-25)
I have heard many sermons on wrestling with God in prayer. In this passage Jacob was wrestling a man. We know that this was no ordinary man, because in Hosea 12:3-4 this passage described Jacob as having 'power over the angel.' We also know this man to be God, since Jacob names the place "Penial" (translator's marginal notes say: The Face of God). Therefore we know the Jacob was really wrestling God. Ultimately, and it goes without saying, God won. However the persistance that Jacob had is exemplary. We can apply this passage in the area of prayer. We need to have a time where we seek God's face and hold on to him, in prayer, begging Him for His blessings, much like Jacob did. Persistant prayer is prevailing prayer. So often we do the work we expect God to answer our prayers on the spot, when God wants us to give more of ourselves to Him before He answers.